Before entering Krebs’s cycle, the pyruvate is first decarboxylated and oxidized into:
UHS 2011
Biology
Bioenergetics
Respiration Mechanism – Glycolysis to Electron Transport Chain
Elimination Tool:
Your statement is only partially accurate. Each pyruvate molecule, a byproduct of glycolysis, goes through a process known as pyruvate decarboxylation prior to entering the Krebs (citric acid) cycle. The mitochondria are where this takes place. However, acetyl-CoA (acetyl coenzyme A) rather than acetic acid is the end product. There are two primary steps involved in converting pyruvate to acetyl-CoA:
Decarboxylation: A two-carbon molecule known as an acetyl group is produced when one of the three carbon atoms in pyruvate is eliminated as carbon dioxide (CO2).
Oxidation: The electrons are moved to NAD+ (nicotinamide adenine dinucleotide) and the remaining two-carbon acetyl group is oxidized, creating NADH. Acetyl-CoA is then created by joining the oxidized acetyl group with coenzyme A.
Your statement is only partially accurate. Each pyruvate molecule, a byproduct of glycolysis, goes through a process known as pyruvate decarboxylation prior to entering the Krebs (citric acid) cycle. The mitochondria are where this takes place. However, acetyl-CoA (acetyl coenzyme A) rather than acetic acid is the end product. There are two primary steps involved in converting pyruvate to acetyl-CoA:
Decarboxylation: A two-carbon molecule known as an acetyl group is produced when one of the three carbon atoms in pyruvate is eliminated as carbon dioxide (CO2).
Oxidation: The electrons are moved to NAD+ (nicotinamide adenine dinucleotide) and the remaining two-carbon acetyl group is oxidized, creating NADH. Acetyl-CoA is then created by joining the oxidized acetyl group with coenzyme A.